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Chlorphenamine is often combined with phenylpropanolamine to form an allergy medication with both antihistamine and decongestant properties, though phenylpropanolamine is no longer available in the US after studies showed it increased the risk of stroke in young women. [7] Chlorphenamine remains available with no such risk.
The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. . However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain phenylephrine HCl 10 mg as the nasal ...
In the 1960s and 70s it was a very common component in over-the-counter sleep aids such as Alva-Tranquil, Dormin, Sedacaps, Sominex, Nytol, and many others. [5] The US Food and Drug Administration (FDA) included it in the list of chemicals and compounds barred from use in over-the-counter (OTC) nighttime sleep aid products in 1989.
The evidence does not report how antihistamines affect women differently than men. [1] Different studies have reported on antihistamine use in children, with various studies finding evidence that certain antihistamines could be used by children 2 years of age, and other drugs being safer for younger or older children. [1]
Superdrug Stores plc (trading as Superdrug) is a health and beauty retailer in the United Kingdom, and the second largest behind Boots UK. The company is owned by AS Watson (Health & Beauty UK) Limited [3] [a] which is part of the A.S. Watson Group. It was acquired as part of the buyout of Kruidvat BV in October 2002.
Cold syrup overdose has been linked to visual and auditory hallucinations as well as rapid involuntary jaw, tongue, and eye movements in children. [ medical citation needed ] Decongestants are possibly harmful to people with high blood pressure or a heart disease because these substances can constrict the blood vessels.
Pheniramine (trade name Avil among others) is an antihistamine with anticholinergic properties used to treat allergic conditions such as hay fever or urticaria.It has relatively strong sedative effects, and may sometimes be used off-label as an over-the-counter sleeping pill in a similar manner to other sedating antihistamines such as diphenhydramine.
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]