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Although many pregnant women with high blood pressure have healthy babies without serious problems, high blood pressure can be dangerous for both the mother and baby. Women with pre-existing, or chronic, high blood pressure are more likely to have certain complications during pregnancy than those with normal blood pressure.
Use in pregnancy may harm the baby and use when breastfeeding is not recommended. [1] It is an angiotensin II receptor blocker and works by blocking the effects of angiotensin II. [6] Telmisartan was patented in 1991 and came into medical use in 1999. [7] It is available as a generic medication. [8]
Its use in preterm labor may allow more time for steroids to improve the baby's lung function and provide time for transfer of the mother to a well qualified medical facility before delivery. [2] It is a calcium channel blocker of the dihydropyridine type. [2] Nifedipine is taken by mouth and comes in fast- and slow-release formulations. [2]
Use appears safe in the latter part of pregnancy and it is not expected to cause problems during breastfeeding. [5] [6] It works by blocking the activation of β-and α-adrenergic receptors. [4] Labetalol was patented in 1966 and came into medical use in 1977. [7] It is available as a generic medication. [5]
Drug treatment options are limited, as many antihypertensives may negatively affect the fetus. ACE inhibitors, angiotensin receptor blockers, and direct renin inhibitors are contraindicated in pregnancy as they are teratogenic. Methyldopa, hydralazine, nifedipine, and labetalol are most commonly used for severe pregnancy hypertension. [7]
5 Breastfeeding. 6 History. 7 References ... thiazides are the least expensive antihypertensive drugs ... effects in some nursing infants and should be administered ...
Propranolol may cause harmful effects for the baby if taken during pregnancy; [7] however, its use during breastfeeding is generally considered to be safe. [8] It is a non-selective beta blocker which works by blocking β-adrenergic receptors. [2] Propranolol was patented in 1962 and approved for medical use in 1964. [9]
Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]