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This is an accepted version of this page This is the latest accepted revision, reviewed on 26 February 2025. Plant species, recreational drug (kratom) Mitragyna speciosa Conservation status Least Concern (IUCN 3.1) Scientific classification Kingdom: Plantae Clade: Tracheophytes Clade: Angiosperms Clade: Eudicots Clade: Asterids Order: Gentianales Family: Rubiaceae Genus: Mitragyna Species: M ...
Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an atypical opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.
7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.
New CDC data in 2024 demonstrates U.S. drug overdose deaths have significantly declined, marking the potential for the first year with fewer than 100,000 fatalities since 2020. [35] The CDC data shows a nearly 17% drop in reported overdose deaths during the 12 months ending in June, totaling 93,087. [ 36 ]
The CDC currently recommends people receive two vaccine doses, the first at ages 12 to 15 months and the second between 4 and 6 years old. One dose is 93% effective, and two doses are 97% effective.
"The CDC milestones have been unchanged for many years," Tsomos tells Yahoo Life, "and these updates are especially important for parents of older children who may not have been assessed according ...
CDC Vaccine Information Statement for MMR Vaccine from April 2012. According to the 1993 amended National Childhood Vaccine Injury Act (NCVIA), a VIS must contain at least the following four components: (1) a description of the benefits of the given vaccine, (2) a description of its risks, (3) information about the National Vaccine Injury Compensation Program (VICP), and (4) other relevant ...