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Mitragyna speciosa is a tropical evergreen tree of the Rubiaceae family (coffee family) native to Southeast Asia. [3] It is indigenous to Cambodia, Thailand, Indonesia, Malaysia, Myanmar, and Papua New Guinea, [4] where its leaves, known as kratom, have been used in herbal medicine since at least the 19th century. [5]
Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an atypical opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.
ACIP statements are official federal recommendations for the use of vaccines and immune globulins in the U.S., and are published by the CDC. ACIP reports directly to the CDC director, although its management and support services are provided by CDC's National Center for Immunization and Respiratory Diseases. [1]
7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
Hepatotoxicity may manifest as triglyceride accumulation, which leads to either small-droplet (microvesicular) or large-droplet (macrovesicular) fatty liver. There is a separate type of steatosis by which phospholipid accumulation leads to a pattern similar to the diseases with inherited phospholipid metabolism defects (e.g., Tay–Sachs disease )
CDC Vaccine Information Statement for MMR Vaccine from April 2012. According to the 1993 amended National Childhood Vaccine Injury Act (NCVIA), a VIS must contain at least the following four components: (1) a description of the benefits of the given vaccine, (2) a description of its risks, (3) information about the National Vaccine Injury Compensation Program (VICP), and (4) other relevant ...
Fentanyl. 2 mg (white powder to the right) is a lethal dose in most people. [1] US penny is 19 mm (0.75 in) wide. A drug overdose (overdose or OD) is the ingestion or application of a drug or other substance in quantities much greater than are recommended. [2] [3] Typically the term is applied for cases when a risk to health is a potential ...
Drugs and other substances that have been associated with significant hepatotoxicity (liver damage). Subcategories. This category has the following 2 subcategories ...