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A problem with illegal cocaine use, especially in the higher volumes used to combat fatigue (rather than increase euphoria) by long-term users, is the risk of ill effects or damage caused by the compounds used in adulteration.
Cocaine is a powerful stimulant known to make users feel energetic, cheerful, talkative, etc. In time, negative side effects include increased body temperature, irregular or rapid heart rate, high blood pressure, increased risk of heart attacks, strokes and even sudden death from cardiac arrest.
Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the World, and it is a serious crime in specific contexts ...
Stimulant use disorder is a type of substance use disorder where the use of stimulants caused clinically significant impairment or distress. It is defined in the DSM-5 as "the continued use of amphetamine-type substances, cocaine, or other stimulants leading to clinically significant impairment or distress, from mild to severe". [1]
These results suggested that this promoter is activated by acute cocaine use and possibly means that the neurons it regulates fire rapidly during acute cocaine exposure, yet are not affected by long-term use. BDNF has been implicated as a critical regulator in drug dependency, and Cdk5 is implicated in the regulation of cell proliferation genes ...
Poison Control said pink cocaine is often used in a party or club setting and can cause a variety of effects including hallucinations, anxiety, elevated body temperature, increased heart rate and ...
Although cocaine use became widespread in the 19th century once it was synthesized into cocaine hydrochloride salts, Europeans knew of the coca plant’s stimulating effects since the early 15th ...
"Substance use pertains to using select substances such as alcohol, tobacco, illicit drugs, etc. that can cause dependence or harmful side effects."On the other hand, substance abuse is the use of drugs such as prescriptions, over-the-counter medications, or alcohol for purposes other than what they are intended for or using them in excessive ...