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Homeobox protein Hox-C6 is a protein that in humans is encoded by the HOXC6 gene. [ 5 ] [ 6 ] [ 7 ] Hox-C6 expression is highest in the fallopian tube and ovary. [ 8 ] HoxC6 has been highly expressed in many types of cancers including prostate, breast, and esophageal squamous cell cancer.
Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in the correct places of the body.
209448 Ensembl ENSG00000180818 ENSMUSG00000022484 UniProt Q9NYD6 P31257 RefSeq (mRNA) NM_017409 NM_010462 RefSeq (protein) NP_059105 NP_034592 Location (UCSC) Chr 12: 53.99 – 53.99 Mb Chr 15: 102.88 – 102.88 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-C10 is a protein that in humans is encoded by the HOXC10 gene. Function This gene belongs to the homeobox ...
This gene and other HOXB genes form a gene cluster on chromosome 17 in the 17q21.32 region. [6] Men who inherit a rare (<0.1% in a selected group of patients without clinical signs of prostate cancer ) genetic variant in HOXB13 (G84E or rs138213197) have a 10-20-fold increased risk of prostate cancer.
It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [7]
Homeobox protein Hox-A9 is a protein that in humans is encoded by the HOXA9 gene. [5] [6] In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic ...
Hox genes are a subset of the homeobox genes. The Hox genes are often conserved across species, so some of the Hox genes of Drosophila are homologous to those in humans. In general, Hox genes play a role of regulating expression of genes as well as aiding in development and assignment of specific structures during embryonic growth.
HOXB6 gene is only expressed in erythroid progenitor cells, which are the precursor to red blood cells used for transport of oxygen and carbon dioxide throughout the body. During development, the formation of the HOX gene factor happens in the first stages of fetal development , namely soon after the establishment of the mesoderm , which is the ...