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The idea of a link between parasite infection and immune disorders was first suggested in 1968 [13] before the advent of large scale DNA sequencing techniques.The original formulation of the hygiene hypothesis dates from 1989, when David Strachan proposed that lower incidence of infection in early childhood could be an explanation for the rise in allergic diseases such as asthma and hay fever ...
A reaction to an excessive desire for a germ-free environment began around 1989, when David Strachan put forth the "hygiene hypothesis" in the British Medical Journal. This hypothesis holds that environmental microbes help develop the human immune system; the fewer germs people are exposed to in early childhood, the more likely they are to ...
A test method is a method for a test in science or engineering, such as a physical test, chemical test, or statistical test. It is a definitive procedure that produces a test result. [ 1 ] In order to ensure accurate and relevant test results, a test method should be "explicit, unambiguous, and experimentally feasible.", [ 2 ] as well as ...
Hygiene is a practice [3] related to lifestyle, cleanliness, health, and medicine. In medicine and everyday life, hygiene practices are preventive measures that reduce the incidence and spread of germs leading to disease. [4] Hygiene practices vary from one culture to another. [5]
Recent research has linked the emerging idea of the hygiene hypothesis to viruses. This hypothesis attempts to explain some of the high incidences of diseases such as asthma [ 24 ] and eczema [ 25 ] in the Western world by Western societies' overuse of antibiotic and antiviral agents.
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The closed testing principle allows the rejection of any one of these elementary hypotheses, say H i, if all possible intersection hypotheses involving H i can be rejected by using valid local level α tests; the adjusted p-value is the largest among those hypotheses.
Occupational hygiene or industrial hygiene (IH) is the anticipation, recognition, evaluation, control, and confirmation (ARECC) of protection from risks associated with exposures to hazards in, or arising from, the workplace that may result in injury, illness, impairment, or affect the well-being of workers and members of the community.