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Overview of signal transduction pathways involved in apoptosis. Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, as in programmed cell death, or may result from factors such as diseases, localized injury, or the death of the organism of which the cells are part.
Programmed cell death (PCD; sometimes referred to as cellular suicide [1]) is the death of a cell as a result of events inside of a cell, such as apoptosis or autophagy. [2] [3] PCD is carried out in a biological process, which usually confers advantage during an organism's lifecycle.
John Foxton Ross Kerr AO (24 January 1934 – 4 June 2024) was an Australian pathologist.He was the first to describe the ultrastructural changes in apoptosis, and could show that they differ significantly from the changes that occur in necrosis, another form of cell death.
The human skull is used universally as a symbol of death. Death is the end of life ; the irreversible cessation of all biological functions that sustain a living organism.
Cell growth plays a crucial role in cell proliferation, regulating cellular homeostasis and cell cycle progression through dynamic changes in cell size. [1] And like DNA damage, it can promote senescence by triggering a prolonged cell cycle arrest. [5]
In law, medicine, and statistics, cause of death is an official determination of the conditions resulting in a human's death, which may be recorded on a death certificate.
Alice May Roberts FRSB (born 19 May 1973) [2] is an English academic, TV presenter and author. Since 2012 she has been Professor of Public Engagement in Science at the University of Birmingham.
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.