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Rod bipolar cells do not synapse directly on to ganglion cells. Instead, rod bipolar cells synapse on to a Retina amacrine cell, which in turn excite cone ON bipolar cells (via gap junctions) and inhibit cone OFF bipolar cells (via glycine-mediated inhibitory synapses) thereby overtaking the cone pathway in order to send signals to ganglion ...
Bipolar cells convey impulses from photoreceptors (rods and cones) to ganglion cells, [6] which in turn transport the visual signals to the brain through the optic nerve. Bipolar cells come in two varieties, having either an on-center or an off-center receptive field, each with a surround of the opposite sign. The off-center bipolar cells have ...
The horizontal cells lie in the outer part of the inner nuclear layer and possess somewhat flattened cell bodies.. Their dendrites divide into numerous branches in the outer plexiform layer, while their axons run horizontally for some distance and finally ramify in the same layer.
The amacrine II cells transfer signals bidirectionally, allowing for impressive synchronization of responses from this network. [2] From this network, the bipolar cells each turn on or off to control the intensity of light perceived, and to contrast between colors. [6] Interconnectivity between Amacrine II cells [2]
Retinal summation describes the relationship between different types of cells in the retina: cone photoreceptor cells, bipolar cells, and ganglion cells.With high retinal summation, a large number of photoreceptor cells converge on a smaller number of bipolar cells in transferring their signals to ganglion cells.
These cells form synapses with photoreceptor cells, and detect the neurotransmitter glutamate via a GPCR signal transduction cascade. The glutamate receptor mGluR6 is located post-synaptically at the tips of the bipolar cell dendrites, and is responsible for initiating a signaling cascade that ultimately controls gating of the TRPM1 channel.
Valve interstitial cells (VIC), cardiac valve interstitial cells, or also known as valvular interstitial cells (VICs), are the most prevalent cells in the heart valve leaflets, which are a type of mesenchymal stem cells (MSCs) and are responsible for maintaining the extracellular matrix that provides the mechanical properties of the heart valve.
In many cases, they are connected to midget bipolar cells, which are linked to one cone each. [ 1 ] These neurons show roughly circular receptive fields with antagonistic center and surround; this property is known as spatial opponency and these neurons are typically divided into ON- or OFF-center, depending on whether they are excited or ...