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1α-Hydroxyvitamin D 5 is a chemical derivative of vitamin D 5.The motive to study 1α-hydroxyvitamin D 5 as a potential pharmaceutical drug stemmed from the tendency of calcitriol, a natural metabolite produced in the kidney, to cause toxic hypercalcemia in patients when dosed at concentrations needed to interrupt prostate cancer cells' cycle and stimulate apoptosis.
The liver is required to transform vitamin D into 25-hydroxyvitamin D. This is an inactive metabolite of vitamin D but is a necessary precursor (building block) to create the active form of vitamin D. [1] The kidneys are responsible for converting 25-hydroxyvitamin D to 1,25-hydroxyvitamin D. This is the active form of vitamin D in the body.
[40] [61] [62] Ultraviolet light alone - sunlight or tanning beds - can raise serum 25(OH)D concentration to a bit higher than 100 nmol/L, but not to a level that causes hypervitaminosis D, the reasons being that there is a limiting amount of the precursor 7-dehydrocholesterol synthesized in the skin and a negative feedback in the kidney ...
Alfacalcidol (or 1-hydroxycholecalciferol) is an analogue of vitamin D used for supplementation in humans and as a poultry feed additive.. Alfacalcidol has a weaker impact on calcium metabolism [3] and parathyroid hormone levels [4] than calcitriol; but significant effects on the immune system, including regulatory T cells. [5]
Decamethylcyclopentasiloxane, also known as D 5 and D5, is an organosilicon compound with the formula [(CH 3) 2 SiO] 5. It is a colorless and odorless liquid that is slightly volatile . [ 5 ]
While men are less likely to develop osteoporosis, it is possible and has been occurring more often in recent years in men over age 65. “Most men should aim for 1,000 - 1,200mg of calcium per ...
Natural Balance began in 1989 when Van Patten was a guest on John Davidson's show. Van Patten had lunch with the show's band drummer, Joey Herrick, [2] who rescued dogs and cats. Van Patten told him when he was a kid he had snakes, alligators, and other animals. The drummer and Van Patten had an idea of making a health food for dogs.
These DNA kits for dogs give you way more information than your dog’s breed composition. Many of the kits can be upgraded to include more health and trait testing or allergy and age tests ...