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A dog displaying a typical clinical picture of visceral leishmaniasis. Canine leishmaniasis (LEESH-ma-NIGH-ah-sis) is a zoonotic disease (see human leishmaniasis) caused by Leishmania parasites transmitted by the bite of an infected phlebotomine sandfly. There have been no documented cases of leishmaniasis transmission from dogs to humans.
Miltefosine, sold under the trade name Impavido among others, is a medication mainly used to treat leishmaniasis and free-living amoeba infections such as Naegleria fowleri and Balamuthia mandrillaris. [4] This includes the three forms of leishmaniasis: cutaneous, visceral and mucosal. [5] It may be used with liposomal amphotericin B or ...
Cutaneous leishmaniasis is the most common form, which causes an open sore at each bite site, which heals in a few months to a year and a half, leaving an unpleasant-looking scar. [2] [3] Diffuse cutaneous leishmaniasis produces widespread skin lesions which resemble leprosy, and may not heal on their own. [3]
Cutaneous leishmaniasis is the most common form of leishmaniasis affecting humans. [4] It is a skin infection caused by a single-celled parasite that is transmitted by the bite of a phlebotomine sand fly .
The parasite which causes leishmaniasis is Leishmania, which is a Trypanosomatida. The disease spreads to humans from sandflies, which act as vectors for the parasite when they bite. [3] Animals (such as dogs and rodents) can be a reservoir for the parasite, spreading it to sandflies, and from sandflies to humans. [4]
Leishmaniasis* is spread by the sandfly, and in the dog as well as human has both cutaneous and visceral forms. The dog is considered to be the reservoir for human disease in the Americas. [28] Babesiosis* is spread by members of the family Ixodidae, or hard ticks. The two species of the genus Babesia that affect dogs are B. canis and B. gibsoni.
Leishmania infantum is the causative agent of infantile visceral leishmaniasis in the Mediterranean region [1] and in Latin America, where it has been called Leishmania chagasi. [ 2 ] [ 3 ] It is also an unusual cause of cutaneous leishmaniasis , [ 4 ] which is normally caused by specific lineages (or zymodemes).
Dogs in endemic areas may benefit from combining vaccination with vector control methods. Palatnik-de-Sousa (2012) reviews the development and efficacy of vaccines for canine leishmaniasis, a severe parasitic disease caused by Leishmania species.
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