Search results
Results from the WOW.Com Content Network
Hydrocodone is only pharmaceutically available as an oral medication. [2] It is well-absorbed, but the oral bioavailability of hydrocodone is only approximately 25%. [4] [5] The onset of action of hydrocodone via this route is 10 to 20 minutes, with a peak effect (T max) occurring at 30 to 60 minutes, [51] and it has a duration of 4 to 8 hours. [2]
The following drugs are controlled by the German Narcotic Drugs Act (German: Betäubungsmittelgesetz or BtMG). Trade and possession of these substances without licence or prescription is considered illegal; prescription is illegal for drugs on Anlage I and II and drugs on Anlage III require a special prescription form.
Vicoprofen is supplied in a fixed dose combination tablet which contains hydrocodone bitartrate, USP 7.5 mg with ibuprofen, USP 200 mg. Additional strengths of generic Vicoprofen are now available, in combinations of 5 mg/200 mg and 10 mg/200 mg respectively. [5]
Each benzhydrocodone/APAP immediate release tablet contains 6.12 mg of benzhydrocodone (equivalent to 6.67 mg of benzhydrocodone hydrochloride) and 325 mg of acetaminophen. The tablets are white, capsule-shaped and are debossed with "KP201" on one side. Dosing should start at one to two tablets every four to six hours, as needed for pain.
Metabolites: Hydromorphone, the major active metabolite, has a 10-33-fold higher binding affinity for the mu-opioid receptor than hydrocodone. It may be up to >100-fold higher in some patients. [ 18 ]
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Help; Learn to edit; Community portal; Recent changes; Upload file
Knoll Pharmaceuticals was a drug development company founded by Albert Knoll and Hans Knoll in Germany in 1886. The company was taken over by German BASF in 1975, which sold it to Abbott Laboratories on 30 June 2002 for $6.9 billion. [1] [2] It was the developer of several drugs:
Norhydrocodone is the major metabolite of the opioid analgesic hydrocodone. [1] It is formed from hydrocodone in the liver via N-demethylation predominantly by CYP3A4. [1] Unlike hydromorphone, a minor metabolite of hydrocodone, norhydrocodone is described as inactive. [2]