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AKT can have a number of downstream effects such as activating CREB, [2] inhibiting p27, [3] localizing FOXO in the cytoplasm, [3] activating PtdIns-3ps, [4] and activating mTOR [3] which can affect transcription of p70 or 4EBP1. [3] There are many known factors that enhance the PI3K/AKT pathway including EGF, [5] shh, [2] IGF-1, [2] insulin ...
IC 50 is a quantitative measure that indicates how much of a particular inhibitory substance (e.g. drug) is needed to inhibit, in vitro, a given biological process or biological component by 50%. [1] The biological component could be an enzyme, cell, cell receptor or microbe. IC 50 values are typically expressed as molar concentration.
Apple A12 and Huawei Kirin 980 mobile processors, both released in 2018, use 7 nm chips manufactured by TSMC. [127] AMD began using TSMC 7 nm starting with the Vega 20 GPU in November 2018, [128] with Zen 2-based CPUs and APUs from July 2019, [129] and for both PlayStation 5 [130] and Xbox Series X/S [131] consoles' APUs, released both in ...
While the MIC is the lowest concentration of an antibacterial or antifungal agent necessary to inhibit visible growth, the minimum bactericidal concentration (MBC) is the minimum concentration of an antibacterial agent that results in bacterial death. It is defined by the inability to re-culture bacteria, and the closer the MIC is to the MBC ...
The London Science Museum contains an exhibit "James Watt's end measuring instrument with micrometer screw, 1776" which the science museum claims is probably the first screw micrometer made. This instrument is intended to measure items very accurately by placing them between the two anvils and then advancing one using a fine micrometer screw ...
Microphysiometry is the in vitro measurement of the functions and activities of life or of living matter (as organs, tissues, or cells) and of the physical and chemical phenomena involved on a very small (micrometer) scale. [1] [2] The term microphysiometry emerged in the scientific literature at the end of the 1980s. [3] [4]
The 10 μm process (10 micrometer process) is the level of MOSFET semiconductor process technology that was commercially reached around 1971, [1] [2] by companies such as RCA and Intel.
[3] 2 0: bit: 10 0: bit 1 bit – 0 or 1, false or true, Low or High (a.k.a. unibit) 1.442695 bits (log 2 e) – approximate size of a nat (a unit of information based on natural logarithms) 1.5849625 bits (log 2 3) – approximate size of a trit (a base-3 digit) 2 1: 2 bits – a crumb (a.k.a. dibit) enough to uniquely identify one base pair ...