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Common side effects include numbness, feeling tired, nausea, diarrhea, and low blood cell counts. [5] [6] Other serious side effects include allergic reactions. [6] [5] Use in pregnancy is known to harm the baby. [5] Oxaliplatin is in the platinum-based antineoplastic family of medications. [7] It is believed to work by blocking the duplication ...
Side effects of thalidomide-induced peripheral neuropathy include sensory symptoms, possible motor impairment, and gastrointestinal and cardiovascular autonomic manifestations. The symptoms of immunomodulatory drugs may dictate whether treatment is continued or discontinued, and they can last long-term after chemotherapy completion.
Oxalate, a metabolite of an anti cancer drug oxaliplatin, has been demonstrated to inhibit prolyl hydroxylase, which endows cold-insensitive human TRPA1 with pseudo cold sensitivity (via reactive oxygen generation from mitochondria). This may cause a characteristic side-effect of oxaliplatin (cold-triggered acute peripheral neuropathy). [34]
Potential protective or attenuating agents include GnRH analogs, where several studies have shown a protective effect in vivo in humans, but some studies show no such effect. Sphingosine-1-phosphate (S1P) has shown similar effect, but its mechanism of inhibiting the sphingomyelin apoptotic pathway may also interfere with the apoptosis action of ...
According to Forbes, there have been 45,000 reported cases of side effects related to fluoroquinolones. 23.1 million patients filled prescriptions for oral flouroquinolones in 2011.
Thyroid tumors, thyroid cancer, and vision changes are also potential side effects of Ozempic, per Novo Nordisk. There is also a risk of eating disorders when taking Ozempic, says Dr. Kumar.
In this form of chemotherapy, commonly used drugs include cisplatin, oxaliplatin, and carboplatin, but several have been proposed or are under development. [1] Addition of platinum-based chemotherapy drugs to chemoradiation in women with early cervical cancer seems to improve survival and reduce risk of recurrence.
The Ozempic Side Effect That No One’s Talking About. Korin Miller. September 19, 2024 at 3:42 PM. ... But, given that this is a drug, there are some potential downsides to consider, too.