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Alanine transaminase (ALT), also known as alanine aminotransferase (ALT or ALAT), formerly serum glutamate-pyruvate transaminase (GPT) or serum glutamic-pyruvic transaminase (SGPT), is a transaminase enzyme (EC 2.6.1.2) that was first characterized in the mid-1950s by Arthur Karmen and colleagues. [1]
ALT is usually found only in the liver. AST is most commonly found in the liver, but also in significant amounts in heart and skeletal muscle. [citation needed] Measurement of ALT and AST were used in diagnosing heart attacks, although they have been replaced by newer enzyme and protein tests that are more specific for cardiac damage.
The ALT levels in hepatitis C rises more than in hepatitis A and B. Persistent ALT elevation more than 6 months is known as chronic hepatitis. Alcoholic liver disease , non-alcoholic fatty liver disease (NAFLD), fat accumulation in liver during childhood obesity, steatohepatitis (inflammation of fatty liver disease) are associated with a rise ...
The proportion of AST to ALT in hepatocytes is about 2.5:1, but because AST is removed from serum by the liver sinusoidal cells twice as quickly (serum half-life t 1/2 = 18 hr) compared to ALT (t 1/2 = 36 hr), so the resulting serum levels of AST and ALT are about equal in healthy individuals, resulting in a normal AST/ALT ratio around 1.
AltGr (also Alt Graph) is a modifier key found on many computer keyboards (rather than a second Alt key found on US keyboards). It is primarily used to type special characters and symbols that are not widely used in the territory where sold, such as foreign currency symbols , typographic marks and accented letters . [ 1 ]
Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase (GOT, SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first described by Arthur Karmen and colleagues in 1954.
Alt+Space then S [notes 10] then Arrow Keys and ↵ Enter (to save new size) Alt+F3 then S then Arrow Keys: Alt+F8 then Arrow Keys / Alt+Right Mouse Button [notes 11] Ctrl+x, then ^ vertically Alt+] (snap window to right half of screen), Alt+[(snap window to left half of screen) Keep window always on top Ctrl+Alt+Esc (toggles on/off) Hide the ...
A non-blank alt attribute on a decorative image results in audible clutter for screen reader users, and irrelevant text inserted into search engine results. Similar problems exist for an image that strictly repeats the information found in nearby text or in a caption. The nearby text is sufficient as the image's alternative text.