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Silver sulfadiazine, sold under the brand Silvadene among others, is a topical antibiotic used in partial thickness and full thickness burns to prevent infection. [1] Tentative evidence has found other antibiotics to be more effective, and therefore it is no longer generally recommended for second-degree (partial-thickness) burns, but is still ...
While the company that makes it does not recommend use during breastfeeding, use is believed to be safe if the baby is otherwise healthy. [2] It is in the sulfonamide class of medications. [1] Sulfadiazine was approved for medical use in the United States in 1941. [1] [5] It is on the World Health Organization's List of Essential Medicines. [6]
The Agency for Toxic Substances and Disease Registry (ATSDR) describes argyria as a "cosmetic problem". [ 64 ] One incident of argyria came to the public's attention in 2008, when a man named Paul Karason , whose skin turned blue from using colloidal silver for over 10 years to treat dermatitis , appeared on NBC's Today show.
Author of The Demon Under the Microscope, a history of the discovery of the sulfa drugs; A History of the Fight Against Tuberculosis in Canada (Chemotherapy) Presentation speech, Nobel Prize in Physiology and Medicine, 1939; The History of WW II Medicine "Five Medical Miracles of the Sulfa Drugs". Popular Science, June 1942, pp. 73–78.
The overall incidence of adverse drug reactions to sulfa antibiotics is approximately 3%, close to penicillin; [3] hence medications containing sulfonamides are prescribed carefully. Sulfonamide drugs were the first broadly effective antibacterials to be used systemically, and paved the way for the antibiotic revolution in medicine.
Many important drugs contain the sulfonamide group. [1] A sulfonamide (compound) is a chemical compound that contains this group. The general formula is R−SO 2 NR'R" or R−S(=O) 2 −NR'R", where each R is some organic group; for example, "methanesulfonamide" (where R = methane, R' = R" = hydrogen) is CH 3 SO 2 NH 2.
Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized with a sulfonamide group. [ 1 ] Powdered sulfanilamide was used by the Allies in World War II to reduce infection rates and contributed to a dramatic reduction in mortality rates compared to ...
The allergies to this drug are not reactions to silver but to sulfadiazine, which is an antibiotic from the group of sulfa drugs, which are well known to cause allergies, sometimes severe. I don't know whether the increase of healing times is a consequence of silver or of sulfadiazine.
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