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The most common adverse effects include abdominal pain, feeling tired, and vaginal bleeding. [8] Serious side effects may include heavy vaginal bleeding, bacterial infection, and, if pregnant, birth defects. [8] When used, appropriate follow-up care needs to be available. [8] [14] Mifepristone is primarily an antiprogestogen. [8]
The mifepristone-misoprostol combination is, by far, the most recommended drug regimen for medical abortions, but other drug combinations are available. Misoprostol alone, without mifepristone, may be used in some circumstances for medical abortion, and has even been demonstrated to be successful in the second trimester. [37]
Examples include the progesterone receptor weak partial agonist mifepristone, the selective progesterone receptor modulator (SPRM) ulipristal acetate, and the silent antagonist aglepristone. [2] [3] In medical abortion, mifepristone is combined with a prostaglandin (e.g., gemeprost), while ulipristal is used for emergency contraception. [4]
The state’s law against mifepristone will take effect from 1 July. The law makes it illegal to “prescribe, dispense, distribute, sell or use any drug for the purpose of procuring or performing ...
The Supreme Court hears arguments on whether to maintain access to abortion pill mifepristone as it weighs a high-stakes challenge to the FDA's drug approval process.
Common abortifacients used in performing medical abortions include mifepristone, which is typically used in conjunction with misoprostol in a two-step approach. [3] Synthetic oxytocin , which is routinely used safely during term labor , is also commonly used to induce abortion in the second or third trimester .
During a news conference at his Mar-a-Lago resort on Thursday, former President Donald Trump would not rule out revoking access to mifepristone, one of the two drugs used in medication abortions.
Instillation abortion is performed by injecting a chemical solution consisting of either saline, urea, or prostaglandin through the abdomen and into the amniotic sac.The cervix is dilated prior to the injection, and the chemical solution induces uterine contractions which expel the fetus. [1]