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Cardiac diastole is the period of the cardiac cycle when, after contraction, the heart relaxes and expands while refilling with blood returning from the circulatory system. [ 1 ] [ 2 ] Both atrioventricular (AV) valves open to facilitate the 'unpressurized' flow of blood directly through the atria into both ventricles, where it is collected for ...
Cardiac cells have two refractory periods, the first from the beginning of phase 0 until part way through phase 3; this is known as the absolute refractory period during which it is impossible for the cell to produce another action potential. This is immediately followed, until the end of phase 3, by a relative refractory period, during which a ...
A Wiggers diagram, named after its developer, Carl Wiggers, is a unique diagram that has been used in teaching cardiac physiology for more than a century. [1] [2] In the Wiggers diagram, the X-axis is used to plot time subdivided into the cardiac phases, while the Y-axis typically contains the following on a single grid: Blood pressure. Aortic ...
When an action potential is generated, the membrane potential rises above this level in five distinct phases. [1] Phase 4: Resting membrane potential remains stable at ≈−90 mV. [1] Phase 0: Rapid depolarisation, shifting the voltage to positive.
Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
Systole (/ ˈ s ɪ s t əl i / SIST-ə-lee) is the part of the cardiac cycle during which some chambers of the heart contract after refilling with blood. [1] Its contrasting phase is diastole, the relaxed phase of the cardiac cycle when the chambers of the heart are refilling with blood.
The isovolumetric contraction phase lasts about 0.05 seconds, [1] but this short period of time is enough to build up a sufficiently high pressure that eventually overcomes that of the aorta and the pulmonary artery upon opening of the semilunar valves. This process, therefore, helps maintain the correct unidirectional flow of blood through the ...
An artificial cardiac pacemaker (or artificial pacemaker, so as not to be confused with the natural cardiac pacemaker) or just pacemaker is an implanted medical device that generates electrical impulses delivered by electrodes to the chambers of the heart either the upper atria, or lower ventricles to cause the targeted chambers to contract and ...