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  2. Hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Hemolytic_anemia

    Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels ...

  3. Microangiopathic hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Microangiopathic_hemolytic...

    Microangiopathic hemolytic anemia may be suspected based on routine medical laboratory tests such as a CBC (complete blood cell count). Automated analysers (the machines that perform routine full blood counts in most hospitals) are designed to flag blood specimens that contain abnormal amounts of red blood cell fragments or schistocytes .

  4. Intravascular hemolysis - Wikipedia

    en.wikipedia.org/wiki/Intravascular_hemolysis

    However, during hyper-hemolytic conditions or with chronic hemolysis, haptoglobin is depleted so the remaining free hemoglobin readily distribute to tissues where it might be exposed to oxidative conditions, [2] thus some of the ferrous heme (FeII), the oxygen-binding component of hemoglobin, of the free hemoglobin are oxidized and becoming met ...

  5. Pyruvate kinase deficiency - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_kinase_deficiency

    Pyruvate kinase deficiency is an inherited metabolic disorder of the enzyme pyruvate kinase which affects the survival of red blood cells. [4] [5] Both autosomal dominant and recessive inheritance have been observed with the disorder; classically, and more commonly, the inheritance is autosomal recessive.

  6. Autoimmune hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_hemolytic_anemia

    A hemolytic state exists whenever the red cell survival time is shortened from the normal average of 120 days. Hemolytic anemia is the hemolytic state in which anemia is present, and bone marrow function is inferentially unable to compensate for the shortened lifespan of the red cell. Immune hemolytic states are those, both anemic and nonanemic ...

  7. Hemolysis - Wikipedia

    en.wikipedia.org/wiki/Hemolysis

    A red blood cell in a hypotonic solution, causing water to move into the cell A red blood cell in a hypertonic solution, causing water to move out of the cell. Hemolysis or haemolysis (/ h iː ˈ m ɒ l ɪ s ɪ s /), [1] also known by several other names, is the rupturing of red blood cells (erythrocytes) and the release of their contents into surrounding fluid (e.g. blood plasma).

  8. Hemoglobin C - Wikipedia

    en.wikipedia.org/wiki/Hemoglobin_C

    The anemia in hemoglobin C disease is classified as hemolytic, because it is caused by the destruction of red blood cells. An enlarged spleen , and sometimes jaundice, may also occur. [ 1 ] [ 3 ] [ 4 ] Some persons with this disease may develop gallstones that require treatment. [ 5 ]

  9. Hexokinase deficiency - Wikipedia

    en.wikipedia.org/wiki/Hexokinase_deficiency

    Hexokinase deficiency manifests is associated with chronic nonspherocytic hemolytic anemia. [3] Hemolytic anemia seems to be the only clinical sign of hexokinase deficiency. [ 4 ] In 1967 the first case of hexokinase deficiency was described by Valentine et al, [ 5 ] since then, less than 50 cases have been reported.