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Onychomycosis, also known as tinea unguium, [4] is a fungal infection of the nail. [2] Symptoms may include white or yellow nail discoloration, thickening of the nail, and separation of the nail from the nail bed . [ 2 ]
Tinea unguium presents a much greater therapeutic challenge as topical creams do not penetrate the nail bed. Historically, systemic griseofulvin treatment showed improvements in some patients with tinea unguium; however, failure was common even in lengthy treatment courses (e.g., > 1 yr).
The experts point to prescription treatments: Topical medications are typically taken for a year, and even pills generally take three months to work. In other words, buckle up for the long haul ...
Treatment of tinea capitis requires an oral antifungal agent; griseofulvin is the most commonly used drug, but other newer antimycotic drugs, such as terbinafine, itraconazole, and fluconazole have started to gain acceptance, topical treatment include selenium sulfide shampoo.
Tinea pedis (athlete's foot): fungal infection of the feet; Tinea unguium: fungal infection of the fingernails and toenails, and the nail bed; Tinea corporis: fungal infection of the arms, legs, and trunk; Tinea cruris : fungal infection of the groin area; Tinea manuum: fungal infection of the hands and palm area
Tinea corpora (body), tinea manus (hands), tinea cruris (groin), tinea pedis (foot) and tinea facie (face) can be treated topically. Tinea unguium (nails) usually will require oral treatment with terbinafine, itraconazole, or griseofulvin. Griseofulvin is usually not as effective as terbinafine or itraconazole.
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