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The most frequently reported drugs that have been associated with the development of AGEP include penicillin, aminopenicillins, macrolides, quinolones, sulfonamides, hydroxychloroquine, terbinafine, and diltiazem. [7] A more complete list of drugs sorted by their intended actions are: [3] [7] [9] [10] [11]
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
Diltiazem has negative inotropic, chronotropic, and dromotropic effects. This means diltiazem causes a decrease in heart muscle contractility – how strong the beat is, lowering of heart rate – due to slowing of the sinoatrial node , and a slowing of conduction through the atrioventricular node – increasing the time needed for each beat.
Osimertinib, sold under the brand name Tagrisso, [6] is a medication used to treat non-small-cell lung carcinomas with specific mutations. [7] [8] It is a third-generation epidermal growth factor receptor tyrosine kinase inhibitor.
The "passivity" agreement FDIC wants BlackRock to sign is designed to assure bank regulators that the giant money manager will remain a "passive" owner of an FDIC-supervised bank and won’t exert ...
Construction adhesive being used to attach an access panel to drywall. The construction adhesive is in a caulking gun at the top of the image. Construction adhesive is a general-purpose adhesive used for attaching drywall , tile , molding , and fixtures to walls, ceilings, and floors. [ 1 ]
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Purvi Parikh, M.D., an allergist with Allergy & Asthma Network, recommends blowing one nostril at a time by putting a finger or pressure on one side of your nose, closing that nostril, and blowing ...