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A small publication of Mukherjee in 1978 [19] clearly shows that Mukherjee was on the right line of thinking much before anyone else had demonstrated the successful outcome of a pregnancy following the transfer of a 8-cell frozen-thawed embryo into human subjects transferring 8-cell cryopreserved embryos. [20] [21]
The cost of the egg-freezing procedure (without embryo transfer) in the United States, the United Kingdom, and other European countries varies in between $5,000 and $12,000. The cost of egg storage can vary from $100 to more than $1,000. Provisional health programs do not cover social egg freezing.
Cryopreservation for embryos is used for embryo storage, e.g., when IVF has resulted in more embryos than is currently needed. One pregnancy and resulting healthy birth has been reported from an embryo stored for 27 years, after the successful pregnancy of an embryo from the same batch three years earlier. [39]
Of the 4.5 million pregnancies that resulted in single deliveries, 4.4 million were naturally conceived, around 78,000 pregnancies were fresh embryo transfers, and around 18,000 pregnancies were ...
Embryo transfer refers to a step in the process of assisted reproduction in which embryos are placed into the uterus of a female with the intent to establish a pregnancy.This technique - which is often used in connection with in vitro fertilization (IVF) - may be used in humans or in other animals, in which situations and goals may vary.
Both preimplantation embryos at various stages and sperm can be used for this purpose. For distribution, cryopreserved samples are typically transported using dry shipper. [51] Among the two methods, sperm cryopreservation offers clear advantages—it is more cost-effective and requires fewer experimental animals than embryo cryopreservation. [52]
The maturation rate correlated with the age of patient and duration of IVM. With the 8 couples with embryo cryopreservation, there was a 65% fertilisation rate. At least one good quality day 3 embryo was cryopreserved in 7/8 couples.
The first transplant of cryopreserved ovarian tissue was performed in New York by Kutluk Oktay in 1999, but it did not restore menstrual cycles to the patient. In 2004 Jacques Donnez in Belgium reported the first successful birth from frozen tissue using a protocol developed in Roger Gosden’s laboratory, where Oktay had studied.
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