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Topical fluorides are fluoride-containing drugs indicated in prevention and treatment of dental caries, particularly in children's primary dentitions. [1] The dental-protecting property of topical fluoride can be attributed to multiple mechanisms of action, including the promotion of remineralization of decalcified enamel, the inhibition of the cariogenic microbial metabolism in dental plaque ...
Fluoride works primarily through direct contact with teeth. [3] [5] Fluoride came into use to prevent tooth decay in the 1940s. [6] Fluoride is on the World Health Organization's List of Essential Medicines. [7] In 2021, it was the 291st most commonly prescribed medication in the United States, with more than 600,000 prescriptions. [8] [9]
Topical fluoride is more highly recommended than systemic intake to protect the surface of the teeth. [126] Topical fluoride is used in toothpaste, mouthwash and fluoride varnish. [125] Standard fluoride toothpaste (1,000–1,500 ppm) is more effective than low fluoride toothpaste (< 600ppm) to prevent dental caries. [127]
A 1930s poster from the Work Projects Administration promoting oral hygiene. Tooth decay is the most common global disease. [14] Over 80% of cavities occur inside fissures in teeth where brushing cannot reach food left trapped after eating and saliva and fluoride have no access to neutralize acid and remineralize demineralized teeth, unlike easy-to-clean parts of the tooth, where fewer ...
Dr. Dean's research on the fluoride-dental caries relationship, published in 1942, included 7,000 children from 21 cities in Colorado, Illinois, Indiana, and Ohio. The study concluded that the optimal amount of fluoride which minimized the risk of severe fluorosis but had positive benefits for tooth decay was 1 mg per day, per adult.
The widespread use of toothpaste and mouthwashes with added fluoride in recent decades appears to have diminished the health benefits of water fluoridation, according to a new study.
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