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Image of CD4 co-receptor binding to MHC (Major Histocompatibility Complex) non-polymorphic region. In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as helper T cells, monocytes, macrophages, and dendritic cells.
The other pseudo-device, the slave, emulates a hardware serial port device, [1] and is used by terminal-oriented programs such as shells (e.g. bash) as a processes to read/write data back from/to master endpoint. [1] PTYs are similar to bidirectional pipes. [3]: 1388 Devpts is a Linux kernel virtual file system containing pseudoterminal devices.
During binding with MHC-II, CD4 maintains independent structure and does not form any bonds with the TCR receptor. The members of the CD family of co-receptors have a wide range of function. As well as being involved in forming a complex with MHC-II with TCR to control T-cell fate, the CD4 receptor is infamously the primary receptor that HIV ...
CD4-Ig works by mimicking the binding of CD4 to HIV, thereby preventing the virus from infecting T-helper cells. HIV infects T-helper cells by binding to the CD4 receptor and the co-receptor CCR5 or CXCR4. CD4-Ig binds to the viral envelope glycoprotein gp120, which is responsible for HIV binding to CD4. By binding to gp120, CD4-Ig prevents the ...
Kermit is a computer file transfer and management protocol and a set of communications software tools primarily used in the early years of personal computing in the 1980s. It provides a consistent approach to file transfer, terminal emulation, script programming, and character set conversion across many different computer hardware and operating system platforms.
A directory is a logical section of a file system used to hold files. Directories may also contain other directories. The cd command can be used to change into a subdirectory, move back into the parent directory, move all the way back to the root directory or move to any given directory.
File descriptors for a single process, file table and inode table. Note that multiple file descriptors can refer to the same file table entry (e.g., as a result of the dup system call [3]: 104 ) and that multiple file table entries can in turn refer to the same inode (if it has been opened multiple times; the table is still simplified because it represents inodes by file names, even though an ...
The N-terminal tail of Lck is myristoylated and palmitoylated, which tethers the protein to the plasma membrane of the cell. The protein furthermore contains a SH3 domain, a SH2 domain and in the C-terminal part the tyrosine kinase domain. The two main phosphorylation sites on Lck are tyrosines 394 and 505.