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ER-positive is one of the Receptor statuses identified in the classification of breast cancer.Receptor status was traditionally considered by reviewing each individual receptor (ER, PR, her2) in turn, but newer approaches look at these together, along with the tumor grade, to categorize breast cancer into several conceptual molecular classes [1] that have different prognoses [2] and may have ...
Traditional screening and diagnostic mammography ("2D mammography") uses x-ray technology and has been the mainstay of breast imaging for many decades. Breast tomosynthesis ("3D mammography") is a relatively new digital x-ray mammography technique that produces multiple image slices of the breast similar to, but distinct from, computed ...
Digital mammography is a specialized form of mammography that uses digital receptors and computers instead of X-ray film to help examine breast tissue for breast cancer. [9] The electrical signals can be read on computer screens, permitting more manipulation of images to allow radiologists to view the results more clearly.
Mammography is widely accepted as the first-line screening option for the detection of breast cancer, with a sensitivity for detection of cancer at around 85-90%. However, in patients with dense breast tissue or those with risk of breast cancer greater than 20%, the sensitivity of mammography drops significantly, with some studies reporting a ...
Breast cancers typically fall into one of four subtypes, based on whether the cancer cells have an overabundance of the HER2 gene, and/or receptors for estrogen (ER-positive), progesterone (PR ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 2 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
Triple-negative breast cancer acts aggressively, grows quickly, spreads further and is more likely to return, the American Cancer Society says. It often occurs in women younger than 40, Black ...
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