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Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. [18] It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in children and adults, but not recommended in elderly patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura ...
Dose de-escalation below the starting doses in case of poor patient's chemotherapy tolerability applies to cyclophosphamide only. If the nadir ANC > 500/μL, then the doses of etoposide, doxorubicin, and cyclophosphamide for the next cycle are all increased by 20% over the doses used in the previous cycle.
The 2023 Nordic Nutrition Recommendations state "Since no safe limit for alcohol consumption can be provided, the recommendation in NNR2023 is that everyone should avoid drinking alcohol." [ 5 ] The American Heart Association recommends that those who do not already consume alcoholic beverages should not start doing so because of the negative ...
Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [ 1 ] [ 2 ] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [ 3 ] [ 4 ] use).
The reinforcing effects of alcohol consumption are mediated by acetaldehyde generated by catalase and other oxidizing enzymes such as cytochrome P-4502E1 in the brain. [60] Although acetaldehyde has been associated with some of the adverse and toxic effects of ethanol, it appears to play a central role in the activation of the mesolimbic ...
The U.S. National Institute on Alcohol Abuse and Alcoholism defines a moderate dose as alcohol intake up to two standard drinks or 28 grams for men and one standard drink or 14 grams for women. [7] The immediate effect of alcohol depends on the drinker's blood alcohol concentration (BAC).
Johnson’s “Nutty Pudding” recipe, which was available at the summit and is a daily part of Johnson’s strict diet, is customizable and can include both macadamia nut and macadamia milk, as ...
Alcohol consumption is associated with lower sperm concentration, percentage of normal morphology, and semen volume, but not sperm motility. [210] Frequent drinking of alcoholic beverages is a major contributing factor in cases of hypertriglyceridemia. [211] Alcoholism is the single most common cause of chronic pancreatitis. [212] [213] [214 ...