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Traditionally, prostate cancer grades were described according to the Gleason Score, a system named for the pathologist who developed it in the 1960s. Dr. Donald Gleason realized that cancerous cells fall into 5 distinct patterns as they change from normal cells to tumor cells.
Based on the Gleason score, prostate cancers are often divided into 3 groups: Cancers with a Gleason score of 6 or less may be called well differentiated or low-grade. Cancers with a Gleason score of 7 may be called moderately differentiated or intermediate-grade.
What is a good Gleason score for prostate cancer? A Gleason score isn’t good or bad, per se. Knowing your Gleason score is one way that healthcare providers predict how quickly prostate cancer might grow. Gleason scores range from 6 (low-grade cancer) to 10 (high-grade cancer).
Learn about prostate cancer biopsies and the Gleason score. Understand how biopsies are performed, the Gleason score, and how it impacts treatment decisions.
The most common scale used to evaluate the grade of prostate cancer cells is called a Gleason score. Gleason scoring combines two numbers and can range from 2 (nonaggressive cancer) to 10 (very aggressive cancer), though the lower part of the range isn't used as often.
Prostate cancer staging is based on how far the cancer has spread as well as the Gleason score and PSA levels. Learn more about prostate cancer stages here.
If the tissue shows prostate cancer, the pathologist grades the most prevalent type of cancer cell on a scale of 3 to 5. The higher the number, the more aggressive the cancer. The pathologist does the same for the second most prevalent type of cancer cell. The sum of the two grades is the Gleason score — for example, 3+3=6, 3+4=7, 4+3=7, 4+4 ...
The diagnosis of prostate cancer is suspected when individuals have a hard enlarged prostate or nodule on physical exam as well as an elevated prostate-specific antigen (PSA) level on laboratory analysis. The diagnosis is confirmed with a biopsy and histologic assessment.
The Gleason score typically ranges from 6 to 10. Scores 2 to 5 are possible but occur so rarely that they do not feature in official classifications. Doctors diagnose prostate cancer by...
According to the NCI, a Gleason score of 6 or lower, a PSA level of 10 ng/ml or less, and an early tumor stage places you in the low-risk category. Together, these factors mean that the...