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Fluorine is often added to drug molecules during drug design, as even a single atom can greatly change the chemical properties of the molecule in desirable ways. Because of the considerable stability of the carbon–fluorine bond , many drugs are fluorinated to delay their metabolism , which is the chemical process in which the drugs are turned ...
Fluorine. cubic. Fluorine is a chemical element; it has symbol F and atomic number 9. It is the lightest halogen [note 1] and exists at standard conditions as pale yellow diatomic gas. Fluorine is extremely reactive as it reacts with all other elements except for the light inert gases.
Chemically, it is 2-deoxy-2- [18F]fluoro-D-glucose, a glucose analog, with the positron -emitting radionuclide fluorine-18 substituted for the normal hydroxyl group at the C-2 position in the glucose molecule. The uptake of [18 F]FDG by tissues is a marker for the tissue uptake of glucose, which in turn is closely correlated with certain types ...
Fluorine compounds. Fluorine forms a great variety of chemical compounds, within which it always adopts an oxidation state of −1. With other atoms, fluorine forms either polar covalent bonds or ionic bonds. Most frequently, covalent bonds involving fluorine atoms are single bonds, although at least two examples of a higher order bond exist. [2]
Fluoride is sold in tablets for cavity prevention. Fluoride or fluorine deficiency is a disorder which may cause increased dental caries [1] and possibly osteoporosis, [2][3] due to a lack of fluoride in diet. [4][5] Common dietary sources of fluoride include tea, grape juice, wine, raisins, some seafood, coffee, and tap water that has been ...
Isotopes of fluorine. Complete table of nuclides. Fluorine-18 (18 F) is a fluorine radioisotope which is an important source of positrons. It has a mass of 18.0009380 (6) u and its half-life is 109.771 (20) minutes. It decays by positron emission 96.7% of the time and electron capture 3.3% of the time. Both modes of decay yield stable oxygen-18.
Fluorine is a relatively new element in human applications. In ancient times, only minor uses of fluorine-containing minerals existed. The industrial use of fluorite, fluorine's source mineral, was first described by early scientist Georgius Agricola in the 16th century, in the context of smelting. The name "fluorite" (and later "fluorine ...
As a result, the physical and chemical properties of organofluorines can be distinctive in comparison to other organohalogens. The carbon–fluorine bond is one of the strongest in organic chemistry (an average bond energy around 480 kJ/mol [ 1 ]). This is significantly stronger than the bonds of carbon with other halogens (an average bond ...