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Oncogene is a peer-reviewed scientific journal published under the Springer Nature addressing cancer cell genetics and the structure and function of oncogenes. The journal has editorial office in London, England. The journal was established in 1987. [1] An open access online-only sister journal, Oncogenesis, was established in 2012 by Douglas R ...
Oncogenesis is a peer-reviewed open access medical journal covering the molecular biology of cancer. It was established in 2012 by Douglas R. Green as a sister journal to Oncogene, of which Green was then editor-in-chief. [1] New articles are published exclusively online by Nature Publishing Group on a weekly basis. [2]
An oncogene is a gene that has the potential to cause cancer. [1] In tumor cells, these genes are often mutated, or expressed at high levels. [2] Most normal cells undergo a preprogrammed rapid cell death (apoptosis) if critical functions are altered and then malfunction.
Oncogenomics. Oncogenomics is a sub-field of genomics that characterizes cancer -associated genes. It focuses on genomic, epigenomic and transcript alterations in cancer. Cancer is a genetic disease caused by accumulation of DNA mutations and epigenetic alterations leading to unrestrained cell proliferation and neoplasm formation.
Myc family: The Myc family of transcription factors are proto-oncogenes implicated in cancer. Yamanaka et al. and Jaenisch et al. demonstrated that c-myc is a factor implicated in the generation of mouse iPS cells and Yamanaka et al. demonstrated it was a factor implicated in the generation of human iPS cells.
Science (journal) Science. (journal) Science is the peer-reviewed academic journal of the American Association for the Advancement of Science [A 2][1] (AAAS) and one of the world's top academic journals. [2] It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000.
The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as indexed by Clarivate's Web of Science. As a journal-level metric, it is frequently used as a proxy for ...
Another studied reprogrammed pathway is gain of function of the oncogene MYC. This gene encodes a transcription factor that boosts the expression of a number of genes involved in anabolic growth via mitochondrial metabolism. [11] Oncometabolite production is another example of metabolic deregulation. [12]