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The urachus forms from the distal end of the allantois in the embryo, and develops into a closed cord between the base of the bladder, and the navel. [1] It drains the bladder of the fetus that joins and runs within the umbilical cord . [ 2 ]
During fetal development, the allantois becomes the urachus, a duct between the bladder and the yolk sac. A patent allantois can result in a urachal cyst. Because the allantois can be cultured ex vivo, it has utility as a model system for studying the formation of blood vessels as well as considerable usefulness in drug screening.
A urachal fistula is a congenital disorder caused by the persistence of the allantois (later, urachus), the structure that connects an embryo's bladder to the yolk sac. Normally, the urachus closes off to become the median umbilical ligament; however, if it remains open, urine can drain from the bladder to an opening by the umbilicus. [1]
4. Urinary bladder. 5. Urachus. cl. Cloaca. cp. Elevation which becomes clitoris or penis. i. Lower part of the intestine. ls. Fold of integument from which the labia majora or scrotum are formed. m, m. Right and left Müllerian ducts uniting together and running with the Wolffian ducts in gc, the genital cord. ot.
If the urachus fails to close during fetal life, it can result in anatomical abnormalities such as a urachal cyst, urachal fistula, urachal diverticulum or urachal sinus. In very rare cases the urachus can fail to close fully. This can lead to a condition known as a patent urachus (also urachal fistula). Although it is mainly immediately ...
The embryonic allantois becomes the fetal urachus, which connects the fetal bladder (developed from cloaca) to the yolk sac. The urachus removes nitrogenous waste from the fetal bladder. [ 13 ] After birth the urachus is closed, and becomes the median umbilical ligament .
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A urachal diverticulum (also vesicourachal diverticulum) is a congenital disorder caused by the partial persistence of the allantois.The allantois, which later becomes the urachus, connects an embryo's bladder to the yolk sac.