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  2. Prednisone - Wikipedia

    en.wikipedia.org/wiki/Prednisone

    Prednisone is absorbed in the gastrointestinal tract and has a half-life of 2–3 hours. [37] it has a volume of distribution of 0.4–1 ... Prednisone 20 mg oral tablet.

  3. Biological half-life - Wikipedia

    en.wikipedia.org/wiki/Biological_half-life

    Absorption half-life 1 h, elimination half-life 12 h. Biological half-life ( elimination half-life , pharmacological half-life ) is the time taken for concentration of a biological substance (such as a medication ) to decrease from its maximum concentration ( C max ) to half of C max in the blood plasma .

  4. Glucocorticoid - Wikipedia

    en.wikipedia.org/wiki/Glucocorticoid

    Then change to oral hydrocortisone or cortisone as a single morning dose, and gradually decrease by 2.5 mg each week. When the morning dose is less than replacement, the return of normal basal adrenal function may be documented by checking 0800 cortisol levels prior to the morning dose; stop drugs when 0800 cortisol is 10 μg/dl.

  5. Methylprednisolone - Wikipedia

    en.wikipedia.org/wiki/Methylprednisolone

    Troleandomycin, ketoconazole, and Clarithromycin inhibit metabolism; and may decrease the rate of elimination and increase the half-life of methylprednisolone. [21] [32] Dosages should be decreased accordingly to avoid side effects. Another CYP 3A4 inhibitor, grapefruit juice, prolongs the half-life of oral methylprednisolone. [32]

  6. Plateau principle - Wikipedia

    en.wikipedia.org/wiki/Plateau_Principle

    The initial concentration of any non-nutritive phytochemical in the blood plasma is zero unless a person has recently ingested a food or beverage. For example, as increasing amounts of green tea extract are consumed, a graded increase in plasma catechin can be measured, and the major compound is eliminated with a half-life of about 5 hours. [13]

  7. Prednisolone - Wikipedia

    en.wikipedia.org/wiki/Prednisolone

    Prednisolone has a relatively short half-life, ranging 2–4 hours. It also has a large therapeutic window , considering the dosage required to produce a therapeutic effect is a few times higher than what the body naturally produces.

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  9. Naproxen - Wikipedia

    en.wikipedia.org/wiki/Naproxen

    Elimination half-life: 12–17 hours ... or steroid medicines such as prednisone. ... time to peak plasma concentration occurs between 2 and 4 hours after oral ...

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