Search results
Results from the WOW.Com Content Network
It is the same molecule as the hormone and neurotransmitter norepinephrine. [2] It is given by slow injection into a vein. [2] Common side effects include headache, slow heart rate, and anxiety. [2] Other side effects include an irregular heartbeat. [2] If it leaks out of the vein at the site it is being given, norepinephrine can result in limb ...
A few endogenous MAEs have been identified, including the trace amines β-phenylethylamine (PEA), tyramine, and tryptamine. [1] [11] At a concentration of 16 μM (1.6 × 10-5 M), β-phenylethylamine has been shown to act as a MAE for norepinephrine (2.6-fold increase), dopamine (1.3-fold increase), and serotonin (2.3-fold increase) in the rat brainstem in vitro.
Examples of sympathomimetic effects include increases in heart rate, force of cardiac contraction, and blood pressure. [1] The primary endogenous agonists of the sympathetic nervous system are the catecholamines (i.e., epinephrine [adrenaline], norepinephrine [noradrenaline], and dopamine ), which function as both neurotransmitters and hormones .
Side effects of droxidopa include headache, dizziness, nausea, and hypertension, among others. [2] Droxidopa is a synthetic amino acid precursor which acts as a prodrug to the neurotransmitter norepinephrine (noradrenaline). [4] Hence, it acts as a non-selective agonist of the α-and β-adrenergic receptors.
Catecholaminergic means "related to catecholamines". The catecholamine neurotransmitters include dopamine , epinephrine (adrenaline), and norepinephrine (noradrenaline). A catecholaminergic agent (or drug ) is a chemical which functions to directly modulate the catecholamine systems in the body or brain.
Ephedrine, one of the most well-known selective NRAs.. A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug that induces the release of norepinephrine (noradrenaline) and epinephrine (adrenaline) from the pre-synaptic neuron into the synapse.
After administering phenylethanolamine to dogs intravenously, these investigators observed that 10–30 mg/kg of the drug increased pupil diameter, and decreased body temperature; a dose of 10 or 17.5 mg/kg decreased heart rate, but a 30 mg/kg dose caused it to increase. Other effects that were noted included profuse salivation and piloerection ...
A catecholamine (/ ˌ k æ t ə ˈ k oʊ l ə m iː n /; abbreviated CA) is a monoamine neurotransmitter, an organic compound that has a catechol (benzene with two hydroxyl side groups next to each other) and a side-chain amine. [1] Catechol can be either a free molecule or a substituent of a larger molecule, where it represents a 1,2 ...