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If subungual melanoma is diagnosed at its final stage, or Stage IV, the survival rate is 15% to 20% at five years and 10% to 15% at 10 years.
What is the survival rate of subungual melanoma? The survival rate is high when subungual melanoma is detected early. Survival rates are about 95% when it’s caught at an early stage and treated quickly.
Subungual melanoma is a distinct subtype of cutaneous malignant melanoma arising from structures within the nail apparatus. It is ordinarily a variant of acral lentiginous melanoma, a malignant melanoma originating on palms and soles.
It’s estimated that there is an average 5-year survival rate of 16 to 80 percent. This wide percentile is attributed to the timing of diagnosis and accounts for delayed diagnosis due...
This 5-year survival rate falls to 74% for melanomas that spread regionally and 35% for melanomas that spread to distant organs.
According to the American Cancer Society, the 5-year survival rate for cutaneous melanoma varies between 15–97% depending on stage. Melanoma of the nail unit may have a worse prognosis compared with cutaneous melanoma, but this may be related to the late presentation.
Pathologic response rates, which were a strong marker for relapse-free survival, were 80% and 77% in arms A and B with complete response rates of 43% and 57%, respectively. Arm C was closed secondary to high toxicity.
Subsequently, subungual melanoma historically has a relatively poor prognosis compared with other cutaneous melanomas, with the 5-year survival rate ranging between 16 and 80 percent. Historically, these lesions were removed using aggressive amputation.
It accounts for about 0.7 to 3.5% of all cutaneous melanomas. Experts are not yet certain of the specific origins of subungual melanoma. However, research suggests that it could be due to an increase in the production of melanin, a substance in your body that produces pigmentation.
The overall 5-year survival rate in this group was 69.5%, but the outlook is much lower for people diagnosed with stage 4 subungual melanoma, at just 15–20%.