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Clonidine, sold under the brand name Catapres among others, is an α 2A-adrenergic receptor agonist [12] medication used to treat high blood pressure, ADHD, drug withdrawal (e.g., alcohol, opioids, or nicotine), menopausal flushing, diarrhea, spasticity, and certain pain conditions. [13]
Clonazepam, sold under the brand name Klonopin among others, is a benzodiazepine medication used to prevent and treat anxiety disorders, seizures, bipolar mania, agitation associated with psychosis, obsessive–compulsive disorder (OCD), and akathisia. [11] It is a long-acting [12] tranquilizer of the benzodiazepine class. [11]
I agree that a lot of people do not understand that Klonopin is a completely different medication than clonadine! Clonidine can indeed be used in the treatment of RLS. I've cited this statement in the article to clarify the point. Thank you for the notification! ― Bio chemistry 🙴 23:37, 3 October 2018 (UTC)
The first ODT form of a drug to get approval from the U.S. Food and Drug Administration (FDA) was a Zydis ODT formation of Claritin in December 1996. [19] It was followed by a Zydis ODT formulation of Klonopin ( clonazepam ) in December 1997, [ 20 ] and a Zydis ODT formulation of Maxalt ( rizatriptan ) in June 1998. [ 21 ]
The evidence suggesting a link between benzodiazepines (and Z-Drugs) and pancreatic inflammation is very sparse and limited to a few observational studies from Taiwan. [159] [160] A criticism of confounding can be applied to these findings as with the other controversial associations above. Further well-designed research from other populations ...
The risk of abuse in this class of medication is smaller than in that of barbiturates. Cognitive and behavioral adverse effects are possible. [32] Benzodiazepines include: alprazolam (Xanax), bromazepam, chlordiazepoxide (Librium), clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), oxazepam, temazepam, and Triazolam.
The drug or other substance has a high potential for abuse. The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug or other substances may lead to severe psychological or physical dependence.
It is an analogue of triazolam, the difference between them being the absence of a chlorine atom in the ortho position of the phenyl ring. [93] It is slightly soluble in chloroform, soluble in alcohol, slightly soluble in acetone and insoluble in water. [94] It has a melting point of 228–229.5 °C (442.4–445.1 °F; 501.1–502.6 K). [94] [95]