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Mascot is a software search engine that uses mass spectrometry data to identify proteins from peptide sequence databases. [1] [2] Mascot is widely used by research facilities around the world.
UniProt Knowledgebase (UniProtKB) is a protein database partially curated by experts, consisting of two sections: UniProtKB/Swiss-Prot (containing reviewed, manually annotated entries) and UniProtKB/TrEMBL (containing unreviewed, automatically annotated entries). [11]
Quantitative proteomics can circumvent these issues, only needing sequence information to be performed. It can be applied on a global proteome level, or on specifically isolating binding partners in pull-down or affinity purification experiments. [4] [22] Disadvantages, however, in sensitivity and analysis time must be kept in consideration. [23]
The human cyclophilin family, as represented by the structures of the isomerase domains of some of its members. A protein family is a group of evolutionarily related proteins.In many cases, a protein family has a corresponding gene family, in which each gene encodes a corresponding protein with a 1:1 relationship.
The DisProt database contains a collection of manually curated protein segments which have been experimentally determined to be disordered. MobiDB is a database combining experimentally curated disorder annotations (e.g. from DisProt) with data derived from missing residues in X-ray crystallographic structures and flexible regions in NMR ...
In enzymology, a xylose isomerase (EC 5.3.1.5) is an enzyme that catalyzes the interconversion of D-xylose and D-xylulose. This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The isomerase has now been observed in nearly a hundred species of bacteria. [2]
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In the episode "Metamorphosis", it is stated that Zefram Cochrane of Alpha Centauri, the discoverer of the space warp, disappeared 150 years ago, at the age of 87. Based on the 2207 to 2212 [ 57 ] date originally given this would have put Cochrane's disappearance between 2057 and 2062 and his birth between 1970 and 1975.