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Rotarix vaccine for oral administration. Rotarix is a monovalent, human, live attenuated rotavirus vaccine containing one rotavirus strain of G1P[8] specificity.Rotarix is indicated for the prevention of rotavirus gastroenteritis caused by G1 and non-G1 types (G3, G4, and G9) when administered as a 2-dose series in infants and children. [19]
The new center will support both domestic and global immunization and respiratory disease prevention and control priorities, and will link epidemiology and laboratory science around vaccine-preventable diseases and acute respiratory infections with prevention and control programs and strong communication science.
Most children admitted to hospital with gastroenteritis are tested for rotavirus. [95] [96] Specific diagnosis of infection with rotavirus is made by finding the virus in the child's stool by enzyme immunoassay. There are several licensed test kits on the market which are sensitive, specific and detect all serotypes of rotavirus. [97]
Rotaviruses, noroviruses, adenoviruses, and astroviruses are known to cause viral gastroenteritis. [26] Rotavirus is the most common cause of gastroenteritis in children, [25] and produces similar rates in both the developed and developing world. [20] Viruses cause about 70% of episodes of infectious diarrhea in the pediatric age group. [13]
Antibiotics will not be effective if the cause of gastroenteritis is a viral infection. Doctors usually do not recommend antidiarrheal medications (e.g., Loperamide) for gastroenteritis because they tend to prolong infection, especially in children. [2] Parasitic infections are difficult to treat. A number of drugs are available once the ...
Acute diarrhea is most commonly due to viral gastroenteritis with rotavirus, which accounts for 40% of cases in children under five. [1] In travelers, however, bacterial infections predominate. [27] Various toxins such as mushroom poisoning and drugs can also cause acute diarrhea.
Infection prevention and control is the discipline concerned with preventing healthcare-associated infections; a practical rather than academic sub-discipline of epidemiology. In Northern Europe , infection prevention and control is expanded from healthcare into a component in public health , known as "infection protection" ( smittevern ...
Each year, prior to 2006, rotavirus was responsible for more than 400,000 doctors visits, more than 200,000 emergency room visits, 55,000 to 70,000 hospitalizations, and 20 to 60 deaths in children under the age of 5. Globally, rotavirus is still the cause of approximately half a million deaths each year in children younger than 5 years of age.