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This classification helps defining the safety requirements necessary to be in line with the ISO 26262 standard. The ASIL is established by performing a risk analysis of a potential hazard by looking at the Severity, Exposure and Controllability of the vehicle operating scenario. The safety goal for that hazard in turn carries the ASIL requirements.
Resistant hypertension: add spironolactone ACC / AHA 2017 [13] General <130/80 BP > 130/80: Lifestyle changes and monotherapy with thiazide-type diuretic, ACEI/ARB, and/or CCB BP >20/10 above target: Lifestyle changes and two from different classes: thiazide-type diuretic, ACEI/ARB, and/or CCB JNC 8 2013 [1] General age ≥60 General age <60 ...
Automotive Safety Integrity Level refers to an abstract classification of inherent safety risk in an automotive system or elements of such a system. ASIL classifications are used within ISO 26262 to express the level of risk reduction required to prevent a specific hazard, with ASIL D representing the highest hazard level and ASIL A the lowest.
Azilsartan, sold under the brand name Edarbi among others, is used for the treatment of hypertension. [2] [3] [4] It is used as the prodrug azilsartan medoxomil, is an angiotensin II receptor antagonist, [5] and was developed by Takeda. The most common adverse reaction in adults is diarrhea. [2] It is available as a generic medication. [6]
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). [1] Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke, heart failure, kidney failure and myocardial infarction.
Some risks associated with stroke are hypertension (high blood pressure), atrial fibrillation (an irregular heartbeat) and smoking, according to the US Centers for Disease Control and Prevention.
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Essential hypertension (also called primary hypertension, or idiopathic hypertension) is a form of hypertension without an identifiable physiologic cause. [1] [2] It is the most common type affecting 85% of those with high blood pressure. [3] [4] The remaining 15% is accounted for by various causes of secondary hypertension. [3]