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Use of antidepressants during pregnancy may result in fetus abnormalities affecting functional development of the brain and behavior. [90] Studies have shown correlations between pregnant women treated with SNRIs and risk of hypertensive disorders, [ 91 ] preeclampsia, [ 92 ] miscarriage, [ 93 ] seizures in children, [ 94 ] and many other ...
A 2012 review focused on antidepressants and sleep found that mirtazapine reduced the time it took to fall asleep and improved the quality of sleep in many people with sleep disorders caused by depression, but that it could also disturb sleep in many people, especially at higher doses, causing restless leg syndrome in 8 to 28% of people and in ...
Antidepressants are recommended by the UK National Institute for Health and Care Excellence (NICE) as a first-line treatment of severe depression and for the treatment of mild-to-moderate depression that persists after conservative measures such as cognitive therapy. [10]
It thus did not recommend duloxetine as a first-line treatment for major depressive disorder, given the (then) high cost of duloxetine compared to inexpensive off-patent antidepressants and lack of increased efficacy. [25] Duloxetine appears less tolerable than some other antidepressants. [26] Generic duloxetine became available in 2013. [27]
The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
Sertraline, sold under the brand name Zoloft among others, is an antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class [10] used to treat major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive–compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder. [11]
Elavil (amitriptyline) – a tricyclic antidepressant used as a first-line treatment for neuropathic pain Eurodin , Prosom ( estazolam ) – a benzodiazepine derivative with anxiolytic , anticonvulsant , hypnotic , sedative and skeletal muscle relaxant properties, commonly prescribed for short-term treatment of insomnia
Nortriptyline may cause problems if taken during pregnancy. [8] Use during breastfeeding appears to be relatively safe. [ 7 ] It is a tricyclic antidepressant (TCA) and is believed to work by altering levels of serotonin and norepinephrine .
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