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Amitriptyline is effective for depression, [23] but it is rarely used as a first-line antidepressant due to its higher toxicity in overdose and generally poorer tolerability. [24] It can be tried for depression as a second-line therapy, after the failure of other treatments. [ 13 ]
The guidelines recommended that antidepressant treatment be considered: For people with a history of moderate or severe depression. For people with mild depression that has been present for an extended period. As a first-line treatment for moderate to severe depression.
Antidepressants are recommended by the UK National Institute for Health and Care Excellence (NICE) as a first-line treatment of severe depression and for the treatment of mild-to-moderate depression that persists after conservative measures such as cognitive therapy. [10]
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Use of antidepressants during pregnancy may result in fetus abnormalities affecting functional development of the brain and behavior. [90] Studies have shown correlations between pregnant women treated with SNRIs and risk of hypertensive disorders, [91] preeclampsia, [92] miscarriage, [93] seizures in children, [94] and many other adverse affects.
Full Antidepressants List: SSRIs, SNRIs, TCAs & Others. Antidepressants: the most common prescription medication among cool people like artists, fictional type As, film protagonists and yourself.
Gestational diabetes is a form of diabetes that is first diagnosed during pregnancy and can accordingly cause high blood sugar that affects the woman and the baby. [9] In 10 - 20% of women whose diet and exercise are not adequate enough to control blood sugar, insulin injections may be required to lower blood sugar levels. [ 9 ]
The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
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