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Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats ...
Evidence of high worm burden is required before a veterinarian can dispense and sell the product, known as 'medicated grit'. [6] However, there has been increasing concern about contaminants entering the ground waters running off from moorlands, as well as from its use in farming environments and its presence in manure .
Both oxfendazole and fenbendazole are efficacious against gastrointestinal lungworms and roundworms of livestock, adults, and L4-larvae of the significant species for example, of the genera Bunostomum, Haemonchus, Ostertagia, Oesophagostomum, Nematodirus, Teladorsagia, Cooperia, Trichostrongylus, Dictyocaulus, Trichuris, etc., including against arrested larvae of some of the species.
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Unlike sheep, cattle can develop sufficient immunoprotection against such parasites. [ 15 ] Both in vitro (egg hatch assay, larval development test, larval motility test, polymerase chain reaction and in vivo methods ( fecal egg count reduction test ) can be used to detect anthelmintic resistance.
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