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The Hox genes, being a subset of homeobox genes, arose more recently in evolution within the animal kingdom or Metazoa. Within the animal kingdom, Hox genes are present across the bilateria [10] (animals with a clear head-to-tail axis), and have also been found in Cnidaria such as sea anemones. [11]
[10] [11] Morphogens in Drosophila include decapentaplegic and hedgehog. [10] During development, retinoic acid, a metabolite of vitamin A, is used to stimulate the growth of the posterior end of the organism. [12] Retinoic acid binds to retinoic acid receptors that acts as transcription factors to regulate the expression of Hox genes. Exposure ...
3211 15407 Ensembl ENSG00000120094 ENSMUSG00000018973 UniProt P14653 P17919 RefSeq (mRNA) NM_002144 NM_008266 RefSeq (protein) NP_002135 NP_032292 Location (UCSC) Chr 17: 48.53 – 48.53 Mb Chr 11: 96.26 – 96.26 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene. Function This gene belongs to the homeobox ...
15394 Ensembl ENSG00000105991 ENSMUSG00000029844 UniProt P49639 P09022 RefSeq (mRNA) NM_153620 NM_005522 NM_010449 NM_001311118 RefSeq (protein) NP_005513 NP_705873 n/a Location (UCSC) Chr 7: 27.09 – 27.1 Mb Chr 6: 52.13 – 52.14 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A1 is a protein that in humans is encoded by the HOXA1 gene. Gene Two transcript ...
From the example above, if the descendant with genes A1 and B underwent another speciation event where gene A1 duplicated, the new species would have genes B, A1a, and A1b. In this example, genes A1a and A1b are symparalogs. [1] Vertebrate Hox genes are organized in sets of paralogs. Each Hox cluster (HoxA, HoxB, etc.) is on a different chromosome.
3200 15400 Ensembl ENSG00000105997 ENSMUSG00000079560 UniProt O43365 P02831 RefSeq (mRNA) NM_030661 NM_153631 NM_153632 NM_010452 RefSeq (protein) NP_109377 NP_705895 NP_034582 Location (UCSC) Chr 7: 27.11 – 27.15 Mb Chr 6: 52.15 – 52.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A3 is a protein that in humans is encoded by the HOXA3 gene. Function In ...
3206 15395 Ensembl ENSG00000253293 ENSMUSG00000000938 UniProt P31260 P31310 RefSeq (mRNA) NM_018951 NM_153715 NM_001122950 NM_008263 RefSeq (protein) NP_061824 NP_001116422 NP_032289 Location (UCSC) Chr 7: 27.17 – 27.18 Mb Chr 6: 52.21 – 52.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-A10 is a protein that in humans is encoded by the HOXA10 gene ...
Homeobox protein Hox-D12 is a protein that in humans is encoded by the HOXD12 gene. [5] [6] [7]This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms.