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Trazodone, sold under many brand names, [1] is an antidepressant medication, [20] used to treat major depressive disorder, anxiety disorders, and insomnia. [20] It is a phenylpiperazine compound of the serotonin antagonist and reuptake inhibitor (SARI) class.
It is both a precursor in the synthesis of aripiprazole and one of its metabolites. [ 1 ] [ 2 ] It is unclear whether 2,3-DCPP is pharmacologically active as a serotonin receptor agonist similar to its close analogue 3-chlorophenylpiperazine ( m CPP), though it has been shown to act as a partial agonist of the dopamine D 2 and D 3 receptors.
GR-55562 is a selective serotonin 5-HT 1B and 5-HT 1D receptor antagonist. [1] It is one of several selective serotonin 5-HT 1B receptor antagonists used in scientific research. [2] [3]
This is a list of adverse effects of the antidepressant trazodone, ... [1] [2] [3] Very common. Very common (>10% incidence) adverse effects include: Blurred vision;
Chemical structure of the serotonin antagonist and reuptake inhibitor trazodone.. Serotonin antagonist and reuptake inhibitors (SARIs) are a class of drugs used mainly as antidepressants, but also as anxiolytics and hypnotics.
PNU-181731 is a drug which acts as an agonist at serotonin 5-HT 2 receptors, [1] [2] with strongest binding affinity for the 5-HT 2C subtype at 4.8nM, and weaker 5-HT 2A affinity of 18nM.
An atypical antidepressant is any antidepressant medication that acts in a manner that is different from that of most other antidepressants. Atypical antidepressants include agomelatine, bupropion, iprindole, mianserin, mirtazapine, nefazodone, opipramol, tianeptine, and trazodone.
Depakote (valproic acid/sodium valproate) – an antiepileptic and mood stabilizer used to treat bipolar disorder, neuropathic pain and others; sometimes called an antimanic medication.