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Osteosclerosis is a disorder characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone.
As a result, normal functioning can be completely or partially inhibited, with the symptoms largely presenting themselves as problems in mobility and muscle contraction as expected from disorders in motor end plates. Neuromuscular junction diseases can also be referred to as end plate diseases or disorders. [citation needed]
Characteristic endobone or "bone-within-bone" appearance in the spine, or "sandwich vertebra" appearance, characterized by dense endplate sclerosis with sharp margins Characteristic endobone or "bone-within-bone" appearance in the pelvis and long bones of extremities where areas of osteosclerosis intermingle with areas of relatively hypodense bone.
The proof of an ongoing pathologic process in a Modic change has been documented by SPECT analysis [Isotope scanning using single positron emission computerized tomography], combined with high-resolution CT imaging. This method has shown high metabolic activity in 96.1% of endplates with Modic change type I and 56% with Modic change type 2. [50]
Degenerative disc disease; Other names: Degenerative disc disorder, intervertebral disc degeneration: Degenerated disc between C5 and C6 (vertebra at the top of the picture is C2), with osteophytes anteriorly (to the left) on the lower portion of the C5 and upper portion of the C6 vertebral body.
Nearly 2.3 million people are estimated to be living with multiple sclerosis around the world, but when Montel Williams received his official diagnosis back in 1999, not much was known about the ...
In the temporomandibular joint, subchondral sclerosis of the mandibular condyle has been described as an early change, condylar flattening as a feature of progressive osteoarthritis, and narrowing of the temporomandibular joint space as a late stage change. [14] A joint space of between 1.5 and 4 mm is regarded as normal. [15] Ankle osteoarthritis.
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