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Glucomannan is a water-soluble polysaccharide that is considered a dietary fiber.It is a hemicellulose component in the cell walls of some plant species. Glucomannan is a food additive used as an emulsifier and thickener.
In enzymology, a mannose isomerase (EC 5.3.1.7) is an enzyme that catalyzes the chemical reaction D-mannose ⇌ {\displaystyle \rightleftharpoons } D-fructose Hence, this enzyme has one substrate , D-mannose , and one product , D-fructose .
Since only GDP-L-gulose (the C5-epimer of GDP-D-mannose) was found in the reaction mixture, it was postulated that the enzyme performs the C5-epimerization prior to the C3-epimerization. However, GDP-D-altrose was recently found as a reaction product, which means that both reaction routes can occur: C5-prior-to-C3 and C3-prior-to-C5.
The 3 substrates of this enzyme are GDP-D-mannose, NAD +, and H 2 O, whereas its 3 products are GDP-D-mannuronate, NADH, and H +. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD + or NADP + as acceptor. The systematic name of this enzyme class is GDP-D-mannose:NAD + 6 ...
I'm trying to figure out why mannose (and xylose) is not included in the frequently-cited list "glucose-fructose-galactose". Compare it for example to the article on glycogen. The current article treats mannose mainly as a molecule; the article on glycogen gives the biological context and the human utility as well, and in plainer language.
The systematic name of this enzyme class is GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming). Other names in common use include guanosine 5'-diphosphate- D -mannose oxidoreductase , guanosine diphosphomannose oxidoreductase , guanosine diphosphomannose 4,6-dehydratase , GDP- D -mannose dehydratase , GDP- D -mannose 4,6 ...
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