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There are also a number of other conditions that affect hands, feet, and parts of the face with associated skin color changes that need to be differentiated from acrocyanosis: Raynaud phenomenon, pernio, acrorygosis, erythromelalgia, and blue finger syndrome. The diagnosis may be challenging in some cases, especially when these syndromes co-exist.
Photographic Comparison of: 1) a canker sore – inside the mouth, 2) herpes labialis, 3) angular cheilitis and 4) chapped lips. [4]Chapped lips (also known as cheilitis simplex [5] or common cheilitis) [6] is characterized by the cracking, fissuring, and peeling of the skin of the lips, and is one of the most common types of cheilitis.
Furthermore, mongolian spots, large birthmarks, and the consumption of food products with blue or purple dyes can also result in the bluish skin tissue discoloration and may be mistaken for cyanosis. [ 2 ] [ 3 ] Appropriate physical examination and history taking is a crucial part to diagnose cyanosis.
Typically the fingers, and, less commonly, the toes, are involved. [1] Rarely, the nose, ears, nipples, or lips are affected. [1] The episodes classically result in the affected part turning white and then blue. [2] Often, numbness or pain occurs. [2] As blood flow returns, the area turns red and burns. [2]
When Smith has an attack, her fingers become white, then yellow and eventually blue. Her toes and ears do the same. If she tries to grab something with her hand, she can’t feel it.
When palpated, the lip may have a texture similar to rubbing the gloved finger along sandpaper. [ 7 ] AC may occur with skin lesions of actinic keratosis or skin cancer elsewhere, particularly on the head and neck [ 6 ] since these are the most sun exposed areas.
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