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David J. Acer (November 11, 1949 – September 3, 1990) was an American dentist who allegedly infected six of his patients, including Kimberly Bergalis, with HIV. [1] The Acer case is considered the first documented HIV transmission from a healthcare worker to a patient in the United States, [2] though the means of transmission remain unknown. [3]
Kimberly Ann Bergalis (January 19, 1968 – December 8, 1991) was an American woman who was one of six patients purportedly infected with HIV by dentist David J. Acer, who was infected with HIV and died of AIDS on September 3, 1990.
Linear gingival erythema (LGE) is a periodontal disorder diagnosed based on distinct clinical characteristics. It was originally thought that LGE was directly associated with HIV, and it was thus called HIV-associated gingivitis (HIV-G).
Nearly 450 patients at a hospital in Massachusetts may have been exposed to HIV, hepatitis B and hepatitis C due to bad practices while their IVs were being administered, according to reports.
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HIV is a retrovirus that primarily infects components of the human immune system such as CD4 + T cells, macrophages and dendritic cells. It directly and indirectly destroys CD4 + T cells. [88] HIV is a member of the genus Lentivirus, [89] part of the family Retroviridae. [90] Lentiviruses share many morphological and biological characteristics.
HIV-SGD is more prevalent in HIV positive children than HIV positive adults, [4] at about 19% and 1% respectively. [1] Unlike other oral manifestations of HIV/AIDS such as Kaposi sarcoma, oral hairy leukoplakia and oral candidiasis, which decreased following the introduction of highly active antiretroviral therapy (HAART), HIV-SGD has increased.
The failure of the experimental vaccines is a massive blow to the medical community, which has hit countless dead ends since the first HIV vaccine trial began 36 years ago.