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Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth, often in the form of hydroxychloroquine sulfate. [3]
Serious side effects include problems with vision, muscle damage, seizures, and low blood cell levels. [ 1 ] [ 4 ] Chloroquine is a member of the drug class 4-aminoquinoline . [ 1 ] As an antimalarial, it works against the asexual form of the malaria parasite in the stage of its life cycle within the red blood cell . [ 1 ]
Hydroxychloroquine (Plaquenil) is another option and is generally considered safer than methotrexate. However, these prescribed drugs have a range of side effects such as nausea , loss of appetite , dizziness , hair loss , stomach aches/cramps , headache , liver toxicity and increased risk of infections .
Pyelonephritis is inflammation that results from a urinary tract infection that reaches the renal pelvis of the kidney. [6] Lupus nephritis is inflammation of the kidney caused by systemic lupus erythematosus (SLE), a disease of the immune system. [7] Athletic nephritis is nephritis resulting from strenuous exercise. [8]
Hydroxychloroquine is an FDA-approved antimalarial used for constitutional, cutaneous, and articular manifestations. Hydroxychloroquine has relatively few side effects, and there is evidence that it improves survival among people who have SLE. [120] Cyclophosphamide is used for severe glomerulonephritis or other organ-damaging complications.
A study confirmed that side effects like pancreatitis and kidney damage are possible while taking GLP-1s like Ozempic. Here's what a doctor wants you to know.
Disease course is variable: ... such as hydroxychloroquine and methotrexate, ... kidney function, liver enzymes and other immunological tests (e.g., ...
Researchers from The Institute of Cancer Research in London have developed a new test that can predict colorectal cancer risk in people with IBD with more than 90% accuracy.