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A normal centenarian brain, cut in the coronal plane (top left) is compared to a brain with LATE-NC (top right). The hippocampi on both sides are atrophic (shrunken) in the brain with LATE-NC. The bottom 3 panels show photomicrographs of a hippocampus with LATE-NC, stained for phosphorylated TDP-43 protein (TDP-43).
The superior longitudinal fasciculus (SLF) is an association tract in the brain that is composed of three separate components. [1] [2] It is present in both hemispheres and can be found lateral to the centrum semiovale and connects the frontal, occipital, parietal, and temporal lobes. [2]
The frontal lobe is located at the front of each cerebral hemisphere and positioned in front of the parietal lobe and above and in front of the temporal lobe.It is separated from the parietal lobe by a space between tissues called the central sulcus, and from the temporal lobe by a deep fold called the lateral sulcus, also called the Sylvian fissure.
Primary age-related tauopathy (PART) is a neuropathological designation introduced in 2014 to describe the neurofibrillary tangles (NFT) that are commonly observed in the brains of normally aged and cognitively impaired individuals that can occur independently of the amyloid plaques of Alzheimer's disease (AD).
The archipallium or primitive ("reptilian") brain, comprising the structures of the brain stem – medulla, pons, cerebellum, mesencephalon, the oldest basal nuclei – the globus pallidus and the olfactory bulbs. The paleopallium or intermediate ("old mammalian") brain, comprising the structures of the limbic system.
This isn’t the first time that better sleep has been linked with a lower risk of dementia: A study published in October even found that people with sleep apnea are more likely to develop dementia.
Poor blood circulation in the brain can disrupt brain structure and function. Researchers believe that numerous factors may play a role in the heart-brain connection, including: chronic inflammation
Older adults who have experienced a traumatic injury after a fall are 21 percent more likely to later receive a diagnosis of Alzheimer’s disease or another related dementia, a new study indicates.