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The burden of the HIV/AIDS pandemic, including mother-to-child transmission of HIV, disproportionately affects low- and middle-income countries, in particular the countries of Southern Africa. [2] The World Health Organization (WHO) estimates that 1.3 million women and girls living with HIV become pregnant each year. [3]
The human immunodeficiency virus (HIV) [8] [9] [10] is a retrovirus [11] that attacks the immune system.It is a preventable disease. [5] There is no vaccine or cure for HIV. It can be managed with treatment and become a manageable chronic health condition. [5]
AZT was also seen to reduce maternal-infant transmission of HIV in a randomized controlled trial, suggesting AZT's post-exposure prophylaxis (PEP) use. [14] Subsequent data show combination antiretroviral therapy is significantly superior than AZT in reducing perinatal transmission rates. [15]
A vertically transmitted infection is an infection caused by pathogenic bacteria or viruses that use mother-to-child transmission, that is, transmission directly from the mother to an embryo, fetus, or baby during pregnancy or childbirth. It can occur when the mother has a pre-existing disease or becomes infected during pregnancy. Nutritional ...
HIV transmission occurs largely through heterosexual intercourse. A greater number of people who get infected with HIV/AIDS are heterosexuals. [73] with two-thirds of AIDS cases in this region attributed to this route. Sex between men is also a significant route of transmission, even though it is heavily stigmatized and illegal in many areas.
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Before tenofovir, a principal part of the clinical pathway for both pre-exposure prophylaxis and post-exposure treatment of mother-to-child transmission of HIV during pregnancy, labor, and delivery and has been proven to be integral to uninfected siblings' perinatal and neonatal development.
Dr. Anthony Fauci, the top U.S. infectious disease expert, said Tuesday the COVID-19 pandemic has diverted scientific and financial resources from the fight against AIDS, seriously impeding global ...