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A significant amount of research has been performed on glycosaminoglycans, especially glucosamine and chondroitin, for the treatment of arthritis.These compounds are commonly marketed as nutritional supplements and numerous 'soft therapeutic claims' are made about their health benefits - especially in aging populations. [1]
Chondroitin sulfate; Dermatan sulfate; Chondroitin as a supplement is now commonly used (often in combination with glucosamine) in treating the joint disease of osteoarthritis. [2] In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine ...
ATC code M01 Anti-inflammatory and antirheumatic products is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Distinguished from chondroitin sulfate by the presence of iduronic acid, although some hexuronic acid monosaccharides may be glucuronic acid. [16] Keratan sulfate: Gal or Gal(6S) GlcNAc or GlcNAc(6S)-Gal(6S)β1-4GlcNAc(6S)β1-3: Keratan sulfate type II may be fucosylated. [21] Heparin: GlcUA or IdoUA(2S) GlcNAc or GlcNS or GlcNAc(6S) or GlcNS(6S)
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Glucosamine is often sold in combination with other supplements such as chondroitin sulfate and methylsulfonylmethane. [citation needed] Glucosamine, along with commonly used chondroitin, is not routinely prescribed to treat people who have symptomatic osteoarthritis of the knee, as there is insufficient evidence that this treatment is helpful ...
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